This course emphasizes the fundamental concepts of disease processes in the tissues with emphasis upon molecular and chemical substrates of tissue insult and trauma. The course examines cellular adaptation to injury, degeneration and necroses, inflammatory mechanisms, healing and repair. Topics covered include fluid and hemodynamic derangement, nutritional disorders, genetic and developmental diseases, immunopathology and neoplasia. Particular focus is upon interactive effects of environment and genotype in the determination of pathologic predisposition and expressions.
COREQUISITES: Cellular, Muscle, Cardiovascular & Respiratory Physiology, General Microbiology